MicroRNA-24 inhibits CDX1 expression in decidual tissues of recurrent spontaneous abortion mice to reduce the abortion risk
نویسندگان
چکیده
منابع مشابه
Immunopathological Aspects of Decidual Tissues in Women with First-Trimester Recurrent Spontaneous Abortion
Background/objective: Studies of the decidual leukocyte populations in women suffering from spontaneous early pregnancy loss may provide insight into immunpathological aspects and even cast light on the etiology of recurrent spontaneous abortion.Methods: In order to clarify the immunological role of endometrial leukocytes in repetitive abortion of unknown etiology, a comparative analysis of phe...
متن کاملAnti-Thyroid Peroxidase and Risk of Recurrent Spontaneous Abortion
Background Approximately 2-4% of all women have recurrent spontaneous abortion (RSA); however, the cause is determined in only 50% of cases. Recent studies have shown an association between thyroid autoantibodies as a sign of thyroid autoimmunity and abortion. The aim of the present study was to determine whether circulating anti-thyroid peroxidase (anti-TPO) was associated with RSA. MaterialsA...
متن کاملThe role of miRNA in Recurrent Spontaneous Abortion
Abortion is a term used for missing of fetus before 20th week of pregnancy, which is a common complication of pregnancy and its aetiology usually remains unknown. Known aetiologies for this phenomenon include structural malformation of uterus, genetic anomalies, autoimmune conditions, endocrine defects, coagulative and trombophilic disorders, polycystic ovary, obesity, and lifestyle. Abortion h...
متن کاملDecreased type V collagen expression in human decidual tissues of spontaneous abortion during early pregnancy.
AIM To provide some insight into the aetiology of spontaneous abortion, the contents of type V collagen was investigated in human decidual tissues in spontaneous abortion and normal pregnancy. METHODS Collagens were extracted from decidual tissues in spontaneous abortion (n = 19) and normal pregnancy (n = 25). The different types of collagen alpha chains were separated by sodium dodecyl sulph...
متن کاملEffectiveness of Leukocyte Immunotherapy in Primary Recurrent Spontaneous Abortion (RSA)
Background: Recurrent spontaneous abortion (RSA) is defined as three or more se-quential abortions before the twentieth week of gestation. There are evidences to sup-port an allo-immunologic mechanism for RSA. One of the methods for treatment of RSA is leukocyte therapy; however there is still controversy about effectiveness of this method. Objectives: To evaluate the effectiveness of leukocyte...
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ژورنال
عنوان ژورنال: Advances in Clinical and Experimental Medicine
سال: 2020
ISSN: 1899-5276
DOI: 10.17219/acem/122173